JOYŌME® - ILLUMINATING DAY SERUM

Face the day brilliantly.

 

Joyōme Illuminating Day Serum features six key ingredients that work together to help reverse the visible signs of aging. Leading-edge peptides relax and soften the appearance of expression lines, Hyaluronic Acid draws in moisture for a plump and volumized look, and Eyeseryl Peptide reduces the appearance of puffiness and dark circles around the eyes.
The Illuminating Day Serum also features a light-reflecting pigment to give skin a glowing, radiant look.

Benefits | Shareables | FAQs | Ingredient Glossary

 
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Top | ShareablesFAQs | Ingredient Glossary

JOYŌME DAY SERUM BENEFITS

JOYŌME DAY SERUM BENEFITS

  • Relaxes and softens the appearance of expression lines like crow’s feet, forehead and smile lines

  • • Adds the appearance of plumpness and volume to tired skin

  • • Minimizes the look of pores for refined skin texture

  • • Enhances brightness and radiance
    • Reduces the appearance of dark circles

  • and eye puffiness
    • Controls oil for a luminous matte finish • Quenches and rehydrates thirsty skin
    • Supports a strong skin barrier to help

  • defend against environmental age accelerators

BRIGHTEN YOUR DAY

The Joyōme Illuminating Day Serum features six active ingredients that work together to help reverse the visible signs of aging. Leading-edge peptides relax and soften the appearance of expression lines, Hyaluronic Acid draws in moisture for a plump and volumized look, and Eyeseryl Peptide reduces the
appearance of puffiness and dark circles around the eyes. The Illuminating Day Serum also features a light-reflecting pigment to give skin a glowing, radiant look.

CONSCIOUSLY CLEAN.

INGREDIENTS YOU'LL LIKE, FOR SKINCARE YOU'LL LOVE
Everyone deserves anti-aging skincare products that are not only exceptionally effective, but also remarkably safe. With Joyōme, we went above and beyond the world’s highest safety standards when deciding what to include in our innovative serums, so you never have to compromise effectiveness for safety.

We don’t compromise on safety—and we don’t compromise on strength. Joyōme's ingredients aren’t only uncommonly clean, they’re uncommonly powerful, producing visible results with carefully selected actives that are as effective as they are safe.

THE OTHER MICROBIOME

Keeping your gut microbiome healthy is crucial to your overall health and happiness. Similarly, your skin’s microbiome—the microbes that live on your skin, rather than inside your body— play a vital role in keeping your skin feeling balanced and
looking beautiful. Keeping your skin’s good and bad microbes in balance can help protect your skin from environmental age accelerators, while also working to keep skin moisturized, youthful-looking, and radiant.

ADVANCED AGING

We’re all born with a flourishing skin microbiome, but age changes the balance of your skin. When we’re young, beneficial microbes abound, resulting in skin that’s luminous, supple, and soft as a baby’s...well, you know. But as we age, the balance of microbes shifts, weakening the skin barrier and leaving skin prone to accelerated aging including uneven texture and loss of moisture.


The key to protecting skin from this natural aging process? Keeping your microbiome in balance with ingredients that impede the adhesion of harmful microbes while helping beneficial ones to flourish.

JOYŌME DAY SERUM ADVANTAGE

  • Argireline Peptide – Reduces the appearance of wrinkles associated with repetitive facial expressions, especially in the forehead and around the eyes

  • Hyaluronic Acid (HA) – Improves the appearance of sagging, drooping skin by helping it to look plump and tight

  • Red Clover – Minimizes the appearance of pores by reducing oil accumulation and pore debris

  • Niacinamide – Helps with skin brightening

  • Eyeseryl Peptide – Reduces the appearance of puffiness and dark circles under the eyes

  • Ceramides – Help to lock in moisture and reduce the appearance of wrinkles

BETTER SKINCARE, FOR BETTER LOOKING SKIN

The average American woman uses 16 beauty products before leaving the house...every day!† That adds up to a lot of time and money, and the worst part is, most of those products don’t even work. They claim to “treat” surface level problems, but they use low-quality ingredients that don’t address the root
causes of an aged appearance.


The truth is, your skin is fighting a constant battle in an effort to maintain a healthy-looking, youthful appearance. At the heart of this battle is your skin’s microbiome. This is the delicate balance of microbes, both good and bad, that live on your skin.
When these microbes are balanced in a beneficial way, they help protect your skin from environmental age accelerators that can affect your skin’s appearance.


The best skincare solution is one that works to balance your skin’s microbiome while also actively fighting signs of aging. Introducing Plexus Joyōme, the revolutionary skincare regimen that uses 11 active ingredients along with a patent-pending
Microbiome Balancing Complex to correct and protect your skin barrier, replenish moisture, renew radiance, and restore a youthful-looking glow. With a simple, two-step regimen, Joy
ōme helps you achieve what some other skincare products can’t – skin that looks and feels absolutely beautiful.


It’s the skincare you’ve been waiting for, and the skin you’ve always wanted.

REAL BENEFITS, DELIVERED
Ingredients do nothing if they’re left resting on the skin’s surface. Other brands struggle to overcome this challenge but Joy
ōme™ utilizes a first-to-market, patented system. The HydraLipid Delivery System increases the absorption of active ingredients, transporting them to where they’re needed most.


Joyōme's HydraLipid Delivery System utilizes highly
absorbable molecules of plant-derived lipids that act as carriers for active ingredients.


Safely transported through the skin’s tough outer layer, Joyōme's anti-aging actives are then released so they can begin fighting the visible signs of aging.


HydraLipid is a natural-origin ingredient derived from green, sustainable processes. It is one of the first natural emulsifying agents on the market and is safer and more gentle compared to other products that use synthetic delivery ingredients.

Top | BenefitsFAQs | Ingredient Glossary

JOYŌME SHAREABLES

 
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Brochure

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Share Guide

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Product Info Sheet

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Ingredient Glossary

 
 

JOYŌME FREQUENTLY ASKED QUESTIONS

What is Joyōme and how is it unique?


Joyōme is a unique, high performance skincare line that combines clinically studied ingredients to correct the visible signs of aging, with a scientifically demonstrated skin
microbiome-balancing complex to protect the skin barrier, resulting in healthy looking, beautiful skin.

Joyōme is the only anti-aging skin care line scientifically demonstrated in an in vitro study to increase skin-nourishing S. epidermidis and decrease the adhesion of skin-damaging S. aureus.




What does “clinically studied” mean?


“Clinically studied” means our ingredients and results are backed by solid, third party clinical studies. All 11 of Joyˉome's active ingredients are included at the same levels that were used in the clinical studies that demonstrated their anti-aging benefits. We have also done our own clinical studies on Joyōme to back up our results and to ensure we provide you with a high-quality product with effective ingredients.




Who is Joyōme intended for?


Joyōme is designed for all skin types and ethnicities. It consists of two products that address all the signs of visible aging including the appearance of lines, wrinkles, brown spots, large pores, redness, loss of elasticity, and lack of radiance, plus dry and rough skin. It is not designed for children. Women who are pregnant or breastfeeding should consult their doctor prior to using Joyōme. If you have a teenager who would like to use the products, please consult your dermatologist.




How do I test Joyōme to see if my skin is sensitive to it?


We recommend doing a patch test with both products prior to using. Test a small, pea-sized amount of product on the lower jaw area. Wait 1-2 minutes before proceeding. If any redness or irritation develops, please discontinue use of the products. Consult your health care professional prior to using any new skin care regimen.




When can I expect to see results using Joyōme?


Joyōme users reported softer, smoother, more moisturized skin, and a more even skin tone within 7 days, and a reduction in the appearance of lines and wrinkles within 14-30 days. Please view our clinical results online.




How long will one bottle of Illuminating Day Serum and one bottle of Intensive Overnight Repair Joyōme last?


Each bottle of Joyōme will last about 60 days if used as directed. Recommended use is three pumps per day of each product applied to the face, neck and around the eye area, avoiding direct contact with the eyes.




How do I use Joyōme in combination with other skincare products?


Joyōme consists of one morning and one evening facial treatment serum designed to be used daily. Each serum should be applied after your existing cleanser and before your moisturizer, and/or foundation, and/or SPF product. They can be layered underneath your eye cream in the morning or night.
Example Routine
Morning:
1. Cleanser
2. Illuminating Day Serum
3. Moisturizer (if needed), SPF, Foundation
Evening:
1. Cleanser
2. Intensive Overnight Repair
3. Moisturizer (if needed)
Consult your healthcare professional if you are using prescription facial products, peels, or other dermatologic procedures before using Joyˉome.




How do I use Joyōme?


Illuminating Day Serum: After cleansing, apply three pumps to the face, neck and eye area in the morning – avoiding direct contact with eyes. We highly recommend using an SPF 45+
after the Illuminating Day Serum.
Intensive Overnight Repair: After cleansing, apply three pumps to the face, neck and eye area in the evening – avoiding direct contact with eyes.
For those sensitive to retinoid products, proceed as follows:
1. Test a small, pea-sized amount of the Intensive Overnight Repair on the lower jaw. Wait one to two minutes before applying more. If any redness, irritation or swelling develops, please discontinue use of the product.
2. Apply the Intensive Overnight Repair every other night for two weeks. This is typically enough time for your skin to adjust to the product. 3. If you experience no irritation, dryness, or peeling, increase use to nightly thereafter.




Can I use Joyōme along with Botox, chemical peels, or other cosmetic procedures?


Yes, using Joyōme is a safe and effective way to help maintain and enhance the results of medical-grade cosmetic procedures. There is no contraindication to using Joyōme alongside neuromodulators (such as Botox) or fillers. Please inform your healthcare professional that you are using Joyōme before receiving chemical peels, dermabrasion, laser treatments, or other cosmetic procedures. Joyōme contains a retinoid ester and alpha hydroxy acids that may increase your skin’s sensitivity. Your healthcare professional may suggest stopping the Intensive Overnight Repair serum for 1-2 weeks prior to and after your cosmetic treatment.




What if I notice color or fragrance changes in the products?


Due to the abundance of natural compounds in our products and the fact that we don’t use artificial dyes, the color and/or fragrance may shift slightly over the shelf life of the product,
without affecting efficacy.




Are Joyōme products safe to use during pregnancy and breastfeeding?


It’s always best to consult your healthcare professional before starting any new regimen if you are pregnant or breastfeeding, including Joyōme.




How does Joyōme rate on the Environmental Working Group (EWG) scale?


The majority of Joyōme ingredients rate a “1” or “2” on the EWG scale.




Are Joyōme products organic?


The majority of our ingredients are sourced from nature, all are non-GMO but are not verified to be organic. We use botanical ingredients as well as strategically selected, high-performance, clinically-tested ingredients proven to show results.




Are Joyōme products natural?


There is no official definition for “natural” in skin care or cosmetics. We are committed to efficacy, health, safety, and exclusion of harmful chemicals while still ensuring high-performance, indulgent skin care. Our Microbiome Balancing Complex, and many of our active ingredients such as cranberry, chicory, rosehips, blackberry, rose, magnolia and camu camu berry, are plant-based or harness the benefits of polyphenols, prebiotics, and antioxidants from nature.




Does Joyōme contain preservatives?


Joyōme contains proven, safe, broad-spectrum cosmetic preservatives such as phenoxyethanol and ethylhexlglycerin to ensure the shelf life and stability of the products, and which are accepted by the European Union safety standards. Joyōme’s scientific board of advisors believe these preservatives are safe and not harmful to the skin microbiome.




What is your ingredient selection policy?


Plexus spent years in the lab creating Joyˉome, carefully choosing ingredients that are effective, and meet our stringent safety requirements; omitting any ingredient with evidence that it may pose a potential health hazard. The formulators behind Joyōme have gone beyond the most stringent European Union safety standards to create products that are safe. Please see our “Absolutely Not” list on the website for a full list of ingredients we’ve left out.




Is Joyōme FDA compliant?


Joyōme complies with all US FDA protocols and Health Canada Standards for cosmetics. Joyōme also goes beyond the most stringent European Union Safety Standards for cosmetics— the strictest in the industry.




Does Joyōme contain fragrances?


Joyōme does not contain synthetic fragrances which are known to be potential allergens and are often made with petrochemicals and phthalates. Instead we use botanically-based, essential oils such as damask rose oil from Bulgaria, and essential oils of vanilla, ylang ylang, lavender, and marjoram that have an uplifting scent and help enhance the beauty of the skin.




Can you tell me about the patented HydraLipid Delivery System in Joyōme?


Joyōme incorporates a patented lipid transport system which has the ability to penetrate the skin’s tough outer layer, delivering active ingredients to where they are needed most. Unlike other delivery systems, the HydraLipid system can transport both oil and water-based actives deeply into the skin. Our lipid transport system is naturally and sustainably sourced, as opposed to traditional delivery systems that use propylene glycol or polyethylene glycol which are derived from petroleum.




Can you tell me how the Joyōme Microbiome Balancing Complex works?


Joyōme contains a patent-pending blend of microbiome activating polyphenols, botanicals and prebiotic fibers scientifically demonstrated to positively shift the balance of your skin microbiome. Joyōme affects the skin microbiome in two ways: first, the Microbiome Balancing Complex stimulates the growth of S. epidermidis, a beneficial microbe that supports a happy and balanced skin microbiome. S. epidermidis also works to replenish the skin barrier, ensuring proper moisture retention and protection from damaging environmental factors that cause irritation, dryness, and a weakened structural network.
Second, beta-glucans (cellular sugars) in the Microbiome Balancing Complex have been shown in in vitro studies to impede the adhesion of S. aureus, a destructive microbe that weakens the skin barrier and accelerates the visible signs of aging by making it susceptible to dryness, dullness, and irritation.




Why is the skin microbiome important?


Products that support and nourish the microbiome are central to Plexus’ approach to health. We recognize the incredible impact that good gut health has on all aspects of our health from digestion and metabolism to immunity and mood. But our microbiome isn’t just inside us – it covers our bodies as well. A properly functioning skin microbiome is critical to protect healthy looking, beautiful skin.




Can you tell me about the retinoid ester in the Intensive Overnight Repair?


Our unique retinoid ester is a next generation, anti-aging ingredient superior to retinol due to its distinct structural difference.
It offers three important benefits over traditional retinol:
1. Because it’s a retinoid ester (versus retinol) it does not need to undergo biochemical changes in order to become active on the skin. This important feature contributes to higher efficacy and less irritation.
2. In addition, our retinoid ester is 10x more stable than retinol, offering potency over a longer period of time, whereas traditional retinol breaks down quickly with light, heat, and time.
3. It has its own unique delivery system (dimethyl isosorbide), which allows it to reach the areas of the skin where it’s needed most.




Can I use Joyōme around the eye area?


Joyōme has been ophthalmologist tested and is safe to use around the eye area. On clean skin, tap the product lightly around the bony area of the eye, avoiding direct contact with the eye.




If someone is concerned that Joyōme may cause irritation, what should they do?


Anyone concerned with experiencing sensitivity to Joyōme products should proceed as follows - First, test a small, pea-sized amount of both serums on the lower jaw and wait one to two minutes. If any redness, irritation or swelling develops, please discontinue use of the
product and contact your healthcare professional. Please contact customer service to notify them of the issue as well.

If no irritiation happens with the patch test, apply the serums every other day/night for two weeks. This is typically enough time for your skin to adjust to the product. If you continue to experience no irritation, dryness, or peeling, increase use to every day thereafter.




Is Joyōme GMO-free?


Yes, Joyōme is free from genetically modified ingredients.




What is phenoxyethanol and why is it an ingredient?


Phenoxyethanol is a preservative used to prevent the growth of mold and bacteria in water-based cosmetics. It is approved and safe for use in skincare.




I see that Red Clover is an ingredient in Joyōme. Can you please tell me more about it?


When selecting ingredients, we take into account peer-reviewed scientific studies, the extensive safety data provided by the ingredient supplier, and industry trade groups such as the AHPA (American Herbal Product Association). Based on the data provided, we have found red clover safe for use topically, both for the face and around the eye area.




Is Joyōme formulated to help with Eczema, acne, rosacea, or other skin conditions?


Joyōme is a premium, anti-aging skincare line designed to address the visible signs of aging. It is not intended to treat, cure or prevent any medical skin condition.




Is Joyōme non-comedogenic or "oil free"?


Joyōme is non-comedogenic. By definition, non-comedogenic means that a product is designed not to clog pores. Not only does Joyōme not clog pores, it contains active ingredients that help minimize the appearance of pores while also providing a mild exfoliating action. However, Joyōme does contain small amounts of some oils such as castor seed, blackberry seed and aromatic essential oils. These oils were chosen specifically because of their skin nourishing benefits or, in the case of the aromatic oils, to lend Joyōme its pleasant scent.




What is the source of the Retinoid Ester in Joyōme?


The source of the Retinoid Ester in Joyōme is proprietary information. It is important to note that the retinoid ester that was chosen for the product does NOT need to undergo biochemical changes in order to become active in the skin. This important feature contributes to higher efficacy and less irritation.




Does Joyōme have SPF?


No, Joyōme does not provide a SPF.




Are Joyōme bottles BPA-free?


Yes, our Joyōme bottles and products are BPA-free.




Is the palm oil in the PM Serum sustainably sourced?


The Palm oil in our PM Serum (part of a potent blend of Vitamin E) is sustainably sourced from Peninsular Malaysia and does not come from palm trees grown on new plantations nor plantations from cleared rain forest.




Has Joyōme been tested on animals?


Joyōme is cruelty-free, meaning our formulas are not tested on animals.




Is Joyōme vegan?


Joyōme does not contain any animal-derived ingredients.




Is Joyōme gluten-free?


Yes, Joyōme is gluten-free.




Does Joyōme contain potential allergens such as soy, nuts, seeds, or dairy?


Here is a list of potential allergens. Please consult your healthcare professional if you are allergic or sensitive to any of the following:
Illuminating Day Serum:
• Castor Seed Oil
• Non-GMO Soy-derived lecithin (although Soy lecithin doesn’t contain the protein responsible for the allergic reaction in soy)
• Essential Oils: Chamomile Flower Oil, Jasmine Oil, Lavender Oil, Marjoram Oil, Sandalwood Oil, Vanilla Fruit Extract, Ylang Ylang Flower Oil
Intensive Overnight Repair:
• Castor Seed Oil
• Shea Nut Butter
• Non-GMO Soy-derived lecithin (although soy lecithin doesn’t contain the protein responsible for the allergic reaction in soy)
• Bakuchiol seed extract (derived from the Indian Babchi plant)
• Damask Rose essential oil





At Joyōme,
We believe that everyone deserves great skincare products that are powerful without compromising
safety. We’ve spent countless hours reviewing ingredients, carefully choosing ones that are effective, and meet our stringent safety requirements.

Joyōme has made a Consciously Clean Promise and is strongly committed to the safety and efficacy of its products. We started by following the ultra-stringent guidelines of the European Union which have banned more than 1,300 ingredients from skin care products.


We then went further by identifying additional ingredients deemed untrustworthy. Joyōme is free from GMO’s, parabens, mineral oils, phthalates, gluten, propylene glycol, formaldehyde, sulfates, BHA, BHT, and synthetic fragrances just to name a few. 

 

Below is a list of some of the ingredients that exceed our uncompromising standards and make Joyōme work.

JOYŌME INGREDIENT GLOSSARY

What is Joyōme and how is it unique?


Joyōme is a unique, high performance skincare line that combines clinically studied ingredients to correct the visible signs of aging, with a scientifically demonstrated skin
microbiome-balancing complex to protect the skin barrier, resulting in healthy looking, beautiful skin.

Joyōme is the only anti-aging skin care line scientifically demonstrated in an in vitro study to increase skin-nourishing S. epidermidis and decrease the adhesion of skin-damaging S. aureus.




What does “clinically studied” mean?


“Clinically studied” means our ingredients and results are backed by solid, third party clinical studies. All 11 of Joyˉome's active ingredients are included at the same levels that were used in the clinical studies that demonstrated their anti-aging benefits. We have also done our own clinical studies on Joyōme to back up our results and to ensure we provide you with a high-quality product with effective ingredients.




Who is Joyōme intended for?


Joyōme is designed for all skin types and ethnicities. It consists of two products that address all the signs of visible aging including the appearance of lines, wrinkles, brown spots, large pores, redness, loss of elasticity, and lack of radiance, plus dry and rough skin. It is not designed for children. Women who are pregnant or breastfeeding should consult their doctor prior to using Joyōme. If you have a teenager who would like to use the products, please consult your dermatologist.




How do I test Joyōme to see if my skin is sensitive to it?


We recommend doing a patch test with both products prior to using. Test a small, pea-sized amount of product on the lower jaw area. Wait 1-2 minutes before proceeding. If any redness or irritation develops, please discontinue use of the products. Consult your health care professional prior to using any new skin care regimen.




When can I expect to see results using Joyōme?


Joyōme users reported softer, smoother, more moisturized skin, and a more even skin tone within 7 days, and a reduction in the appearance of lines and wrinkles within 14-30 days. Please view our clinical results online.




How long will one bottle of Illuminating Day Serum and one bottle of Intensive Overnight Repair Joyōme last?


Each bottle of Joyōme will last about 60 days if used as directed. Recommended use is three pumps per day of each product applied to the face, neck and around the eye area, avoiding direct contact with the eyes.




How do I use Joyōme in combination with other skincare products?


Joyōme consists of one morning and one evening facial treatment serum designed to be used daily. Each serum should be applied after your existing cleanser and before your moisturizer, and/or foundation, and/or SPF product. They can be layered underneath your eye cream in the morning or night.
Example Routine
Morning:
1. Cleanser
2. Illuminating Day Serum
3. Moisturizer (if needed), SPF, Foundation
Evening:
1. Cleanser
2. Intensive Overnight Repair
3. Moisturizer (if needed)
Consult your healthcare professional if you are using prescription facial products, peels, or other dermatologic procedures before using Joyˉome.




How do I use Joyōme?


Illuminating Day Serum: After cleansing, apply three pumps to the face, neck and eye area in the morning – avoiding direct contact with eyes. We highly recommend using an SPF 45+
after the Illuminating Day Serum.
Intensive Overnight Repair: After cleansing, apply three pumps to the face, neck and eye area in the evening – avoiding direct contact with eyes.
For those sensitive to retinoid products, proceed as follows:
1. Test a small, pea-sized amount of the Intensive Overnight Repair on the lower jaw. Wait one to two minutes before applying more. If any redness, irritation or swelling develops, please discontinue use of the product.
2. Apply the Intensive Overnight Repair every other night for two weeks. This is typically enough time for your skin to adjust to the product. 3. If you experience no irritation, dryness, or peeling, increase use to nightly thereafter.




Can I use Joyōme along with Botox, chemical peels, or other cosmetic procedures?


Yes, using Joyōme is a safe and effective way to help maintain and enhance the results of medical-grade cosmetic procedures. There is no contraindication to using Joyōme alongside neuromodulators (such as Botox) or fillers. Please inform your healthcare professional that you are using Joyōme before receiving chemical peels, dermabrasion, laser treatments, or other cosmetic procedures. Joyōme contains a retinoid ester and alpha hydroxy acids that may increase your skin’s sensitivity. Your healthcare professional may suggest stopping the Intensive Overnight Repair serum for 1-2 weeks prior to and after your cosmetic treatment.




What if I notice color or fragrance changes in the products?


Due to the abundance of natural compounds in our products and the fact that we don’t use artificial dyes, the color and/or fragrance may shift slightly over the shelf life of the product,
without affecting efficacy.




Are Joyōme products safe to use during pregnancy and breastfeeding?


It’s always best to consult your healthcare professional before starting any new regimen if you are pregnant or breastfeeding, including Joyōme.




How does Joyōme rate on the Environmental Working Group (EWG) scale?


The majority of Joyōme ingredients rate a “1” or “2” on the EWG scale.




Are Joyōme products organic?


The majority of our ingredients are sourced from nature, all are non-GMO but are not verified to be organic. We use botanical ingredients as well as strategically selected, high-performance, clinically-tested ingredients proven to show results.




Are Joyōme products natural?


There is no official definition for “natural” in skin care or cosmetics. We are committed to efficacy, health, safety, and exclusion of harmful chemicals while still ensuring high-performance, indulgent skin care. Our Microbiome Balancing Complex, and many of our active ingredients such as cranberry, chicory, rosehips, blackberry, rose, magnolia and camu camu berry, are plant-based or harness the benefits of polyphenols, prebiotics, and antioxidants from nature.




Does Joyōme contain preservatives?


Joyōme contains proven, safe, broad-spectrum cosmetic preservatives such as phenoxyethanol and ethylhexlglycerin to ensure the shelf life and stability of the products, and which are accepted by the European Union safety standards. Joyōme’s scientific board of advisors believe these preservatives are safe and not harmful to the skin microbiome.




What is your ingredient selection policy?


Plexus spent years in the lab creating Joyˉome, carefully choosing ingredients that are effective, and meet our stringent safety requirements; omitting any ingredient with evidence that it may pose a potential health hazard. The formulators behind Joyōme have gone beyond the most stringent European Union safety standards to create products that are safe. Please see our “Absolutely Not” list on the website for a full list of ingredients we’ve left out.




Is Joyōme FDA compliant?


Joyōme complies with all US FDA protocols and Health Canada Standards for cosmetics. Joyōme also goes beyond the most stringent European Union Safety Standards for cosmetics— the strictest in the industry.




Does Joyōme contain fragrances?


Joyōme does not contain synthetic fragrances which are known to be potential allergens and are often made with petrochemicals and phthalates. Instead we use botanically-based, essential oils such as damask rose oil from Bulgaria, and essential oils of vanilla, ylang ylang, lavender, and marjoram that have an uplifting scent and help enhance the beauty of the skin.




Can you tell me about the patented HydraLipid Delivery System in Joyōme?


Joyōme incorporates a patented lipid transport system which has the ability to penetrate the skin’s tough outer layer, delivering active ingredients to where they are needed most. Unlike other delivery systems, the HydraLipid system can transport both oil and water-based actives deeply into the skin. Our lipid transport system is naturally and sustainably sourced, as opposed to traditional delivery systems that use propylene glycol or polyethylene glycol which are derived from petroleum.




Can you tell me how the Joyōme Microbiome Balancing Complex works?


Joyōme contains a patent-pending blend of microbiome activating polyphenols, botanicals and prebiotic fibers scientifically demonstrated to positively shift the balance of your skin microbiome. Joyōme affects the skin microbiome in two ways: first, the Microbiome Balancing Complex stimulates the growth of S. epidermidis, a beneficial microbe that supports a happy and balanced skin microbiome. S. epidermidis also works to replenish the skin barrier, ensuring proper moisture retention and protection from damaging environmental factors that cause irritation, dryness, and a weakened structural network.
Second, beta-glucans (cellular sugars) in the Microbiome Balancing Complex have been shown in in vitro studies to impede the adhesion of S. aureus, a destructive microbe that weakens the skin barrier and accelerates the visible signs of aging by making it susceptible to dryness, dullness, and irritation.




Why is the skin microbiome important?


Products that support and nourish the microbiome are central to Plexus’ approach to health. We recognize the incredible impact that good gut health has on all aspects of our health from digestion and metabolism to immunity and mood. But our microbiome isn’t just inside us – it covers our bodies as well. A properly functioning skin microbiome is critical to protect healthy looking, beautiful skin.




Can you tell me about the retinoid ester in the Intensive Overnight Repair?


Our unique retinoid ester is a next generation, anti-aging ingredient superior to retinol due to its distinct structural difference.
It offers three important benefits over traditional retinol:
1. Because it’s a retinoid ester (versus retinol) it does not need to undergo biochemical changes in order to become active on the skin. This important feature contributes to higher efficacy and less irritation.
2. In addition, our retinoid ester is 10x more stable than retinol, offering potency over a longer period of time, whereas traditional retinol breaks down quickly with light, heat, and time.
3. It has its own unique delivery system (dimethyl isosorbide), which allows it to reach the areas of the skin where it’s needed most.




Can I use Joyōme around the eye area?


Joyōme has been ophthalmologist tested and is safe to use around the eye area. On clean skin, tap the product lightly around the bony area of the eye, avoiding direct contact with the eye.




If someone is concerned that Joyōme may cause irritation, what should they do?


Anyone concerned with experiencing sensitivity to Joyōme products should proceed as follows - First, test a small, pea-sized amount of both serums on the lower jaw and wait one to two minutes. If any redness, irritation or swelling develops, please discontinue use of the
product and contact your healthcare professional. Please contact customer service to notify them of the issue as well.

If no irritiation happens with the patch test, apply the serums every other day/night for two weeks. This is typically enough time for your skin to adjust to the product. If you continue to experience no irritation, dryness, or peeling, increase use to every day thereafter.




Is Joyōme GMO-free?


Yes, Joyōme is free from genetically modified ingredients.




What is phenoxyethanol and why is it an ingredient?


Phenoxyethanol is a preservative used to prevent the growth of mold and bacteria in water-based cosmetics. It is approved and safe for use in skincare.




I see that Red Clover is an ingredient in Joyōme. Can you please tell me more about it?


When selecting ingredients, we take into account peer-reviewed scientific studies, the extensive safety data provided by the ingredient supplier, and industry trade groups such as the AHPA (American Herbal Product Association). Based on the data provided, we have found red clover safe for use topically, both for the face and around the eye area.




Is Joyōme formulated to help with Eczema, acne, rosacea, or other skin conditions?


Joyōme is a premium, anti-aging skincare line designed to address the visible signs of aging. It is not intended to treat, cure or prevent any medical skin condition.




Is Joyōme non-comedogenic or "oil free"?


Joyōme is non-comedogenic. By definition, non-comedogenic means that a product is designed not to clog pores. Not only does Joyōme not clog pores, it contains active ingredients that help minimize the appearance of pores while also providing a mild exfoliating action. However, Joyōme does contain small amounts of some oils such as castor seed, blackberry seed and aromatic essential oils. These oils were chosen specifically because of their skin nourishing benefits or, in the case of the aromatic oils, to lend Joyōme its pleasant scent.




What is the source of the Retinoid Ester in Joyōme?


The source of the Retinoid Ester in Joyōme is proprietary information. It is important to note that the retinoid ester that was chosen for the product does NOT need to undergo biochemical changes in order to become active in the skin. This important feature contributes to higher efficacy and less irritation.




Does Joyōme have SPF?


No, Joyōme does not provide a SPF.




Are Joyōme bottles BPA-free?


Yes, our Joyōme bottles and products are BPA-free.




Is the palm oil in the PM Serum sustainably sourced?


The Palm oil in our PM Serum (part of a potent blend of Vitamin E) is sustainably sourced from Peninsular Malaysia and does not come from palm trees grown on new plantations nor plantations from cleared rain forest.




Has Joyōme been tested on animals?


Joyōme is cruelty-free, meaning our formulas are not tested on animals.




Is Joyōme vegan?


Joyōme does not contain any animal-derived ingredients.




Is Joyōme gluten-free?


Yes, Joyōme is gluten-free.




Does Joyōme contain potential allergens such as soy, nuts, seeds, or dairy?


Here is a list of potential allergens. Please consult your healthcare professional if you are allergic or sensitive to any of the following:
Illuminating Day Serum:
• Castor Seed Oil
• Non-GMO Soy-derived lecithin (although Soy lecithin doesn’t contain the protein responsible for the allergic reaction in soy)
• Essential Oils: Chamomile Flower Oil, Jasmine Oil, Lavender Oil, Marjoram Oil, Sandalwood Oil, Vanilla Fruit Extract, Ylang Ylang Flower Oil
Intensive Overnight Repair:
• Castor Seed Oil
• Shea Nut Butter
• Non-GMO Soy-derived lecithin (although soy lecithin doesn’t contain the protein responsible for the allergic reaction in soy)
• Bakuchiol seed extract (derived from the Indian Babchi plant)
• Damask Rose essential oil





JOYŌME ILLUMINATING DAY SERUM